Hazes lab publications




43) Genomic analysis of the vaccinia virus strain variants found in dryvax vaccine.
Qin L, Upton C, Hazes B, Evans DH. J Virol. 2011 85(24):13049-60, 2011.

42) The first Ig domain of KIR3DL1 contacts MHC class I at a secondary site.
Fu L, Hazes B, Burshtyn DN. J Immunol. 187(4):1816-25, 2011.

41) Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1.
Campbell S, Hazes B, Kvansakul M, Colman P, Barry M. J Biol Chem. 285(7):4695-708, 2009.

40) Towards a systems biology approach to study type II/IV secretion systems.
Hazes B, Frost L. Biochim Biophys Acta. 1778(9):1839-50, 2008.

39) Development of protein nanotubes from a multi-purpose biological structure.
Audette GF, Hazes B. J Nanosci Nanotechnol. 7(7):2222-9, 2007.

38) Combinatorial dispensing as a fast and efficient means to create complex screens.
Hazes B. Comb Chem High Throughput Screen. 9(10):785-90, 2006.

37) Crystal structures of a poxviral glutaredoxin in the oxidized and reduced states show redox-correlated structural changes.
Bacik JP, Hazes B. J Mol Biol. 365(5):1545-58, 2006.

36) Purification, kinetic characterization, and mapping of the minimal catalytic domain and the key polar groups of Helicobacter pylori alpha-(1,3/1,4)-fucosyltransferases.
Ma B, Audette GF, Lin S, Palcic MM, Hazes B, Taylor DE. J Biol Chem. 281(10):6385-94, 2006.

35) Purification, crystallization and preliminary diffraction studies of an ectromelia virus glutaredoxin.
Bacik JP, Brigley AM, Channon LD, Audette GF, Hazes B. Acta Crystallogr Sect F Struct Biol Cryst Commun. 61(Pt 6):550-2, 2005.

34) F-like type IV secretion systems encode proteins with thioredoxin folds that are putative DsbC homologues.
Elton TC, Holland SJ, Frost LS, Hazes B. J Bacteriol. 187(24):8267-77, 2005.

33) A single aromatic amino acid at the carboxyl terminus of Helicobacter pylori {alpha}1,3/4 fucosyltransferase determines substrate specificity.
Ma B, Lau LH, Palcic MM, Hazes B, Taylor DE. J Biol Chem. 280(44):36848-56, 2005.

32) A nanovolume crystallization robot that creates its crystallization screens on-the-fly.
Hazes B, Price L. Acta Crystallogr D Biol Crystallogr. 61(Pt 8):1165-71, 2005.

31) A modified vapor-diffusion crystallization protocol that uses a common dehydrating agent.
Dunlop KV, Hazes B. Acta Crystallogr D Biol Crystallogr. 61(Pt 8):1041-8, 2005.

30) Epitope mapping of Ly-49G and G-like receptors: CK-1 antibody defines a polymorphic site of functional interaction with class I ligand.
Osman MS, Silver ET, Varghese JC, Chang CS, Gong DE, Audette GF, Hazes B, Kane KP. J Leukoc Biol. 77(5):644-51, 2005.

29) Pros and cons of cryocrystallography: should we also collect a room-temperature data set?
Dunlop KV, Irvin RT, Hazes B. Acta Crystallogr D Biol Crystallogr. 61(Pt 1):80-7, 2004.

28) Crystallization and preliminary diffraction studies of TraF, a component of the Escherichia coli type IV secretory system.
Audette GF, Holland SJ, Elton TC, Manchak J, Hayakawa K, Frost LS, Hazes B. Acta Crystallogr D Biol Crystallogr. 60(Pt 11):2025-7, 2004.

27) Crystallographic analysis of the Pseudomonas aeruginosa strain K122-4 monomeric pilin reveals a conserved receptor-binding architecture.
Audette GF, Irvin RT, Hazes B. Biochemistry. 43(36):11427-35, 2004.

26) Reciprocal transfer of class I MHC allele specificity between activating Ly-49P and Ly-49W receptors by exchange of beta 4-beta 5 loop residues.
Ma BJ, Silver ET, Hazes B, Kane KP. J Immunol. 171(10):5337-44, 2003.

25) When less is more: a more efficient vapour diffusion crystallisation protocol.
Dunlop KV, Hazes B. Acta Cryst D. Acta Cryst. D59, 1797-1800, 2003. (PDF)
Copyright © International Union of Crystallography Acta Cryst. D59, 1797-1800

24) Purification, crystallization and preliminary diffraction studies of the Pseudomonas aeruginosa strain K122-4 monomeric pilin.
Audette GF, Irvin RT, Hazes B. Acta Cryst. D59, 1665-1667, 2003. (PDF)
Copyright © International Union of Crystallography Acta Cryst. D59, 1665-1667

23) C-terminal amino acids of Helicobacter pylori alpha1,3/4 fucosyltransferases determine type I and type II transfer.
Ma B, Wang G, Palcic MM, Hazes B, Taylor DE. J. Biol. Chem. 278, 21893-21900, 2003. (PDF)
Copyright © Journal of Biological Chemistry

22) Allelic variation in the ectodomain of the inhibitory Ly-49G2 receptor alters its specificity for allogeneic and xenogeneic ligands.
Silver ET, Lavender KJ, Gong DE, Hazes B, Kane KP. J Immunol. 169, 4752-4760, 2002. (PDF)
Copyright © Journal of Immunology

21) Specificity and function of activating Ly-49 receptors.
Kane KP, Silver ET, Hazes B. Immunol Rev. 181, 104-114, 2001. (PDF)
Copyright © Immunology Reviews

20) Structure of a pilin monomer from Pseudomonas aeruginosa: implications for the assembly of pili.
Keizer DW, Slupsky CM, Kalisiak M, Campbell AP, Crump MP, Sastry PA, Hazes B, Irvin RT, Sykes BD. J Biol Chem. 276, 24186-24193, 2001. (PDF)
Copyright © Journal of Biological Chemistry

19) Ly-49W, an activating receptor of nonobese diabetic mice with close homology to the inhibitory receptor Ly-49G, recognizes H-2D(k) and H-2D(d).
Silver ET, Gong D, Hazes B, Kane KP. J Immunol. 166, 2333-2341, 2001. (PDF)
Copyright © Journal of Immunology

18) Crystal structure of Pseudomonas aeruginosa PAK pilin suggests a main-chain-dominated mode of receptor binding.
Hazes B, Sastry PA, Hayakawa K, Read RJ, Irvin RT. J Mol Biol. 299, 1005-1017, 2000. (PDF)
Copyright © Journal of Molecular Biology

17) Inactive conformation of the serpin alpha(1)-antichymotrypsin indicates two-stage insertion of the reactive loop: implications for inhibitory function and conformational disease.
Gooptu B, Hazes B, Chang WS, Dafforn TR, Carrell RW, Read RJ, Lomas DA. Proc Natl Acad Sci USA 97, 67-72, 2000. (PDF) NOTE: Gooptu & Hazes, shared first authorship
Copyright © Proceedings of the National Academy of Science, USA

16) A 2.6 A structure of a serpin polymer and implications for conformational disease.
Huntington JA, Pannu NS, Hazes B, Read RJ, Lomas DA, Carrell RW. J Mol Biol. 293, 449-455, 1999. (PDF)
Copyright © Journal of Molecular Biology

15) Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold.
Hagen FK, Hazes B, Raffo R, deSa D, Tabak LA. J Biol Chem. 274, 6797-6803, 1999. (PDF)
Copyright © Journal of Biological Chemistry

14) Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3.
Ling H, Boodhoo A, Hazes B, Cummings MD, Armstrong GD, Brunton JL, Read RJ. Biochemistry. 37, 1777-1788, 1998. (PDF)
Copyright © Biochemistry

13) Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells.
Hazes B, Read RJ. Biochemistry. 36, 11051-11054, 1997. (PDF)
Copyright © Biochemistry

12) Aerolysin and pertussis toxin share a common receptor-binding domain.
Rossjohn J, Buckley JT, Hazes B, Murzin AG, Read RJ, Parker MW. EMBO J. 16, 3426-3434, 1997. (PDF)
Copyright © EMBO Journal

11) Nitrate binding to Limulus polyphemus subunit type II hemocyanin and its functional implications.
Hazes B, Magnus KA, Kalk KH, Bonaventura C, Hol WG. J Mol Biol. 262, 532-541, 1996. (PDF)
Copyright © Journal of Molecular Biology

10) The (QxW)3 domain: a flexible lectin scaffold.
Hazes B. Protein Sci. 5, 1490-1501, 1996.

9) Crystal structure of the pertussis toxin-ATP complex: a molecular sensor.
Hazes B, Boodhoo A, Cockle SA, Read RJ. J Mol Biol. 258, 661-671, 1996. (PDF)
Copyright © Journal of Molecular Biology

8) A mosquitocidal toxin with a ricin-like cell-binding domain.
Hazes B, Read RJ. Nat Struct Biol. 2, 358-359, 1995.

7) Crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences.
Magnus KA, Hazes B, Ton-That H, Bonaventura C, Bonaventura J, Hol WG. Proteins. 19, 302-309, 1994.

6) Evolution of arthropod hemocyanins and insect storage proteins (hexamerins).
Beintema JJ, Stam WT, Hazes B, Smidt MP. Mol Biol Evol. 11, 493-503, 1994. (PDF)
Copyright © 1994 by the Society for Molecular Biology and Evolution

5) Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
Hazes B, Magnus KA, Bonaventura C, Bonaventura J, Dauter Z, Kalk KH, Hol WG. Protein Sci. 2, 597-619, 1993.

4) Effects of changing the interaction between subdomains on the thermostability of Bacillus neutral proteases.
Eijsink VG, Vriend G, van der Vinne B, Hazes B, van den Burg B, Venema G. Proteins. 14, 224-236, 1992.

3) Comparison of the hemocyanin beta-barrel with other Greek key beta-barrels: possible importance of the "beta-zipper" in protein structure and folding.
Hazes B, Hol WG. Proteins. 12, 278-298, 1992.

2) Crystallization properties and structure of Panulirus interruptus haemocyanin.
Wichertjes T, Keegstra W, Neuteboom B, Hazes B, Beintema JJ, van Bruggen EF. Eur J Biochem. 184, 287-296, 1989.

1) Model building of disulfide bonds in proteins with known three-dimensional structure.
Hazes B, Dijkstra BW. Abstract Model building of disulfide bonds in proteins with known three-dimensional structure. Protein Eng. 2, 119-125, 1988.